Problem installing SQL Server 2008 R2 Failover Cluster on Node 2

Exception from HRESULT: 0x80070006

HRESULT: 0x80070006 (E_HANDLE)) ---> System.Runtime.InteropServices.COMException (0x80070006): The handle is invalid. (Exception from HRESULT: 0x80070006 (E_HANDLE)). noted in SQL Server 2008 versions.

The problem rarely occurs in a row. So restart the server. Restart the SQL node two installation.

you can also try removing the traces of SQL installation from the second node and then try setup again. This time it should go.

for SQL instance removal failure try SQL installed instance removal